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N-Leucyl-O-benzyl-hydroxylamin, also known as L-leucine benzyl ester hydroxamate, is a synthetic chemical compound with the molecular formula C16H24N2O3. It is a derivative of hydroxamic acid, featuring a hydroxamate group (-CO-NH-OH) and a leucine residue, which is an essential amino acid. The benzyl group (C6H5-CH2-) is attached to the oxygen atom of the hydroxamate group, providing steric hindrance and affecting the compound's reactivity. N-Leucyl-O-benzyl-hydroxylamin is often used in organic synthesis and as a building block for the preparation of various pharmaceuticals and bioactive molecules. It is also employed in the synthesis of peptidomimetics, which are compounds that mimic the structure and function of peptides. The presence of the hydroxamate group makes it a potential candidate for metal chelation, which can be useful in various chemical and biological applications.

1145-82-0

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1145-82-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1145-82-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1145-82:
(6*1)+(5*1)+(4*4)+(3*5)+(2*8)+(1*2)=60
60 % 10 = 0
So 1145-82-0 is a valid CAS Registry Number.

1145-82-0Downstream Products

1145-82-0Relevant articles and documents

Synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives

Mai, Anh Hung,Pawar, Sonalika,De Borggraeve, Wim M.

, p. 4664 - 4666 (2014)

Different approaches for the synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives from simple amino acids have been investigated. A library of 33 precursors for the preparation of N-hydroxy pyrazinones was obtained in moderate to good yields.

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