114517-02-1

Basic information

• Product Name: Fosquidone
• Synonyms: Fosquidone
• CAS NO: 114517-02-1
• Molecular Formula: C28H22NO6P
• Molecular Weight: 499.457
• Mol File: 114517-02-1.mol

Chemical Properties

• Boiling Point: 729.4°Cat760mmHg
• Flash Point: 394.9°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 2.47E-22mmHg at 25°C
• Refractive Index: 1.7
• CAS DataBase Reference: Fosquidone(CAS DataBase Reference)
• NIST Chemistry Reference: Fosquidone(114517-02-1)
• EPA Substance Registry System: Fosquidone(114517-02-1)

Safety Data

• Hazardous Substances Data: 114517-02-1(Hazardous Substances Data)

Usage

Uses

Antineoplastic.

InChI:InChI=1/C28H22NO6P/c1-17-20-11-6-5-10-19(20)14-29-15-22-25(26(17)29)27(30)21-12-7-13-23(24(21)28(22)31)35-36(32,33)34-16-18-8-3-2-4-9-18/h2-13,15,17H,14,16H2,1H3,(H,32,33)

Relevant articles and documents

Isoquinoline derivatives and their use as anti-cancer agents

There are provided compounds of the general formula (1) STR1 (wherein R1 and R2, which may be the same or different, each represents a hydrogen atom, a hydroxyl group or a group --OP(O) (OH) (OR4) [where R4 represents a hydrogen atom or an alkyl (optionally substituted by a hydroxyl, alkoxy, cyclic ether or cycloalkyl group), alkenyl cycloalkyl, aryl, aralkyl or aroylalkyl group], with the proviso that at least one of R1 and R2 represents a group --OP(O) (OH) (OR4); and R3 represents a hydrogen or halogen atom or a methyl group), and salts thereof. The novel compounds exhibit interesting anti-cancer activity.