114524-91-3Relevant academic research and scientific papers
SYNTHESIS OF PEPTIDE AND GLYCOPEPTIDE FRAGMENTS OF BACTERIAL CELL WALLS
Jezek, Jan,Straka, Radovan,Krchnak, Viktor,Ryba, Milos,Rotta, Jiri,et al.
, p. 1609 - 1624 (2007/10/02)
Peptides, ranging from tetrapeptide I, II to octadecapeptide XXI and from N-acetylmuramylhexapeptide XXIII to tris(N-acetylmuramyl)-octadecapeptide XXVII, were prepared using synthesis in solution as well as solid-phase synthesis.H-L-Ala-D-i-Gln-L-Lys-D-Ala-(L-Ala)2-OMe (VIII) and its lysine-acetylated analogue X were pyrogenic and the former (VIII) exhibited weak immunoadjuvant activity.The immunoadjuvant activity of tris-(N-acetylmuramyl)-octadecapeptide XXVII was comparable with that of MDP and the compound was not pyrogenic.
