114529-53-2Relevant academic research and scientific papers
Biotransformations of acyclic terpenoids, (±)-trans-Nerolidol and geranylacetone, by Glomerella cingulata
Miyazawa, Mitsuo,Nankai, Hirokazu,Kameoka, Hiromu
, p. 1543 - 1547 (2007/10/03)
Microbial transformations of (±)-trans-nerolidol and geranylacetone were carried out with a plant pathogenic fungus, Glomerella cingulata. (±)-trans-Nerolidol and geranylacetone were hydrated at a remote double bond as the main metabolic pathway. A large amount of (E)-3,7,11-trimethyl-1,6-dodecadiene-3,11-diol and small amount of (E)-3,7,11-trimethyl-1,6-dodecadiene-3,10,11-triol were obtained from (±)-trans-nerolidol. Geranylacetone was transformed to (E)-10-hydroxy-6,10-dimethyl-5-undecen-2-one as the major metabolite. (E)-9,10-Dihydroxy-6,10-dimethyl-5-undecen-2-one, (E)-6,10-dimethyl-5,9-undecadien-2-ol, (E)-6,10-dimethyl-5-undecene-2,9,10-triol, and (E)-6,10-dimethyl-5-undecene-2,10-diol were also obtained from geranylacetone. The structures of metabolic products were determined by spectroscopic data.
