1145663-19-9Relevant academic research and scientific papers
Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential
Kamal, Ahmed,Rajender,Reddy, D. Rajasekhar,Reddy, M. Kashi,Balakishan,Shaik, T. Basha,Chourasia, Mukesh,Sastry, G. Narahari
experimental part, p. 1557 - 1572 (2009/08/15)
C2-Fluoro substituted DC-81, and its dimers that comprise of two C2-fluoro substituted DC-81 subunits tethered to their C8-position through simple alkane spacers as well as piperazine moiety side-armed with symmetrical alkyloxy spacers have been designed
C2-FLUORO SUBSTITUTED PIPERAZINE LINKED PYRROLO[2,1-C][1,4] BENZODIAZEPINE DIMERS AND A PROCESS FOR THE PREPARATION THEREOF
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Page/Page column 20, (2009/10/22)
The present invention provides a compounds of general formula IXa-d, useful as potential antitumour agents and pharmaceutical composition comprising these compounds exhibits binding affinity with calf thymus (CT) DNA at a molar ratio of 1:5 in aqueous sod
