1145673-19-3

Upstream product

• 1251834-01-1 C₄₄H₅₈N₆O₇ 

Downstream Products

• 1251833-30-3 4-(((6S,9aS)-1-(benzylcarbamoyl)-8-((3-acetyl-1-methyl-1H-indol-7-yl)methyl)-2-allyl-octahydro-4,7-dioxo-1H-pyrazino[2,1-c][1,2,4]triazin-6-yl)methyl)phenyl dihydrogen phosphate 

Relevant academic research and scientific papers

NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF

Disclosed are novel reverse turn mimetics based on the framework of pyrazino-triazinone, and the use thereof in the treatment of cancers, particularly, acute myeloid leukemia. A method is also provided for manufacturing the reverse turn mimetics on a mass scale.

NOVEL COMPOUNDS OF REVERSE-TURN MIMETICS, METHOD FOR MANUFACTURING THE SAME AND USE THEREOF

Disclosed are novel reverse turn mimetics based on the framework of pyrazino-triazinone, and the use thereof in the treatment of cancers, particularly, acute myeloid leukemia. A method is also provided for manufacturing the reverse turn mimetics on a mass scale.

NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF (3)

Conformationally constrained compounds that are novel and mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins and having bicyclic framework are disclosed, as well as their prodrugs. Such reverse-turn mimetic