114582-75-1Relevant articles and documents
Total synthesis of (±)-mycothiazole and formal enantioselective approach
Le Flohic, Alexandre,Meyer, Christophe,Cossy, Janine
, p. 339 - 342 (2005)
(Chemical Equation Presented) A total synthesis of (±)-mycothiazole and a formal enantioselective approach have been achieved from 2,4-dibromothiazole. A chain extension of a homoallylic alcohol proceeding through an unsaturated sultone intermediate, generated by ring-closing metathesis, was used as a key step for the elaboration of the conjugated (Z)-dienol moiety.