114586-19-5

Upstream product

• 66215-71-2 2-(2-tritylamino-thiazol-4-yl)-(Z)-2-methoxyiminoacetic acid 

Downstream Products

• 122692-95-9 (3S,7aR)-6-{2-[(Z)-Methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetyl}-2,2-dimethyl-5-oxo-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid 2,2-dimethyl-propionyloxymethyl ester 
• 122692-96-0 (3S,7aR)-6-{2-[(Z)-Methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetyl}-2,2-dimethyl-5-oxo-hexahydro-imidazo[5,1-b]thiazole-3-carboxylic acid 4-methoxy-benzyl ester 

Relevant academic research and scientific papers

BICYCLIC IMIDAZOLIDINONES AS POTENTIAL ANTIBIOTICS

The bicyclic imidazolidinones 5 topologically related to the penicillin family, are susceptible to form a stable carbamate with serine-D,D-peptidases.A series of N-7 acylated or sulfonylated (2R,5R)-3,3-dimethyl-8-oxo-4-thia-7,1-diazabicyclooctane-2-carboxylates 12-21 have been prepared.None of these novel penicillin analogs exhibited antibacterial activity.