1146-66-3

Basic information

• Product Name: 2-AMINOHEPTAFLUORONAPHTALENE
• Synonyms: 2-AMINOHEPTAFLUORONAPHTALENE;2-AMINOHEPTAFLUORONAPHTHALENE;2-Aminoheptafluoronaphtalene 97%;2-Aminoheptafluoronaphtalene97%;1,3,4,5,6,7,8-Heptafluoronaphthalen-2-ylamine;2-Aminoheptafluoronaphthalene 97%;1,3,4,5,6,7,8-Heptafluoronaphthalen-2-amine;2-Aminoheptafluoronaphthalene97%
• CAS NO: 1146-66-3
• Molecular Formula: C₁₀H₂F₇N
• Molecular Weight: 269.12
• Mol File: 1146-66-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 71-72
• Boiling Point: 291.3 °C at 760 mmHg
• Flash Point: >110
• Appearance: /
• Density: 1.732 g/cm³
• Vapor Pressure: 0.00197mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: 2-AMINOHEPTAFLUORONAPHTALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOHEPTAFLUORONAPHTALENE(1146-66-3)
• EPA Substance Registry System: 2-AMINOHEPTAFLUORONAPHTALENE(1146-66-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 1146-66-3(Hazardous Substances Data)

Usage

General Description

2-Aminoheptafluoronaphthalene is a chemical compound with the molecular formula C10H5F7N. It is a white to light yellow solid with a strong odor and is insoluble in water. This chemical is used as a fluorophore in the field of chemistry and biochemistry, where it is employed as a fluorescent dye to label and study biomolecules such as proteins, nucleic acids, and lipid membranes. It is also used in the synthesis of various organic compounds and as a reagent in chemical reactions. Additionally, 2-Aminoheptafluoronaphthalene has potential applications in the development of advanced materials and devices due to its unique fluorescent properties. However, it is important to handle and use this chemical with caution due to its potential health hazards and environmental impact.

InChI:InChI=1/C10H2F7N/c11-3-1-2(4(12)8(16)7(3)15)6(14)10(18)9(17)5(1)13/h18H2

Upstream product

• 119-64-2 tetralin 
• 122-78-1 phenylacetaldehyde 
• 1150-36-3 (1,3,4,5,6,7,8-heptafluoronaphthalen-2-yl)hydrazine 
• 86769-21-3 acetophenone 1,3,4,5,6,7,8-heptafluoro-2-naphthylhydrazone 
• 313-72-4 octafluoronaphthalene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1252614-38-2 N-(1,3,4,5,6,7,8-Heptafluoro-2-naphthyl)-3,4,5,6-tetrafluorophthalamic acid 
• 71153-99-6 2,3,4,5,6-Pentafluoro-N-(1,3,4,5,6,7,8-heptafluoro-naphthalen-2-yl)-benzimidoyl chloride 
• 86769-24-6 1,3,4,5,6,7,8-heptafluoro-N-(α-methyl-benzylidene)-2-naphthylamine 
• 27041-17-4 2-Bromo-1,3,4,5,6,7,8-heptafluoronaphthalene 

Relevant articles and documents

Photoassisted Charge Transfer Between DMF and Substrate: Facile and Selective N,N-Dimethylamination of Fluoroarenes

A reversible Van der Waals complex formation between the electron-deficient fluorinated aromatic ring and N,N-dimethylformamide (DMF) molecules followed by light irradiation resulted in charge transfer (CT) process. The complex was stabilized by ammonium formate and further decomposed to form the C?N bond. Control experiments revealed that the simultaneous SNAr pathway also contributes to product formation. This methodology is mild, metal-free, and effective for the amination of a variety of substrates. The reproducibility of this methodology was also verified on gram-scale reactions. The CT states were supported by control UV/Vis spectroscopy and computational studies.

PARTIALLY FLUORINATED HETEROCYCLIC COMPOUNDS. PART 24. A PLAUSIBLE MECHANISM FOR THE FORMATION OF THE FISCHER INDOLE PRODUCT FROM ACETOPHENONE 1,3,4,5,6,7,8,-HEPTAFLUORO-2-NAPHTHYLHYDRAZONE IN WHICH o-FLUORINE IS LOST

Acetophenone 1,3,4,5,6,7,8,-heptafluoro-2-naphthylhydrazone (1) reacts in tetralin at reflux to give 4,5,6,7,8,9,-hexafluoro-2-phenylbenzindole (2) as the major product, accompanied by other materials including acetophenone 3,4,5,6,7,8,-hexafluoro-2-naphthylhydrazone (4) which is proposed as the true precursor to the Fischer indole product (2) since it gives (2) under the same conditions.The presence of α-tetralone in the reaction mixture provides the clue to a reductive elimination of F- from (1).

Partially Fluorinated Heterocyclic Compounds. Part 18. Formation of Fischer Indole Products from Acetophenone 1,3,4,5,6,7,8-Heptafluoro-2-naphthylhydrazone and Acetophenone Pentafluorophenylhydrazone. The Surprising Loss of o-Fluorine

Acetophenone 1,3,4,5,6,7,8-heptafluoro-2-naphthylhydrazone (2) and acetophenone pentafluorophenylhydrazone (3) react in tetralin at reflux temperature to give among the products 4,5,6,7,8,9-hexafluoro-2-phenylbenzindole (6) and 4,5,6,7-tetrafluoro-2-ph