114607-86-2Relevant academic research and scientific papers
Biotransformations Using Clostridia: Stereospecific Reductions of a β-Keto Ester
Christen, Markus,Crout, David H. G.,Holt, Robert A.,Morris, J. Gareth,Simon, Helmut
, p. 491 - 493 (2007/10/02)
The reduction of methyl 4-(4-chlorophenylthio)-3-oxobutanoate 1 by clostridia has been studied.Clostridium pasteurianum ATCC 6013, C. tyrobutyricum DSM 1460 and C. kluyveri NClB 10680 gave the D-(3S) reduction product 2, whereas C. kluyveri DSM 555 gave t
Biotransformation in Organic Synthesis: Applications of Yeast Reduction in the Synthesis of 3,5-Dihydroxy Esters of High Optical Purity
Christen, Markus,Crout, David H. G.
, p. 264 - 266 (2007/10/02)
All four stereoisomers of methyl 6-(p-chlorophenylthio)-3,5-dihydroxyhexanoate have been synthesised by a route in which the key introduction of chirality was effected by an appropriate yeast reduction.
