1146209-50-8 Usage
Description
SCH 2047069 is a chemical compound that demonstrates potent and selective inhibitory activity against the enzyme poly (ADP-ribose) polymerase (PARP)-1. This enzyme plays a crucial role in DNA repair and has been associated with various disease pathologies, such as cancer and inflammatory diseases. SCH 2047069 has shown promise in preclinical studies as a potential therapeutic agent for the treatment of these conditions, with its selective targeting of PARP-1 making it a candidate for further development as a novel drug.
Uses
Used in Pharmaceutical Industry:
SCH 2047069 is used as a potential therapeutic agent for the treatment of cancer and inflammatory disorders due to its selective inhibitory activity against PARP-1. Its ability to target this enzyme may offer new treatment options for patients suffering from these diseases.
Used in Cancer Treatment:
SCH 2047069 is used as an anticancer agent, targeting the PARP-1 enzyme involved in DNA repair. By inhibiting PARP-1, it may disrupt the DNA repair mechanisms in cancer cells, leading to cell death and potentially offering a new approach to cancer therapy.
Used in Inflammatory Disease Treatment:
SCH 2047069 is used as an anti-inflammatory agent, as the PARP-1 enzyme has also been implicated in inflammatory disease pathologies. Its inhibitory effect on PARP-1 may help in reducing inflammation and managing the symptoms of inflammatory disorders.
Used in Drug Development:
SCH 2047069 is used as a candidate for further development as a novel drug. Its selective targeting of PARP-1 and the promising results from preclinical studies make it a valuable compound for the development of new therapeutic agents for the treatment of cancer and inflammatory diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1146209-50-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,2,0 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1146209-50:
(9*1)+(8*1)+(7*4)+(6*6)+(5*2)+(4*0)+(3*9)+(2*5)+(1*0)=128
128 % 10 = 8
So 1146209-50-8 is a valid CAS Registry Number.
1146209-50-8Relevant articles and documents
SPIRO-CONDENSED 1, 3, 4-THIADIAZOLE DERIVATIVES FOR INHIBITING KSP KINESIN ACTIVITY
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Page/Page column 349-350, (2009/05/28)
The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising t
