1146216-59-2Relevant academic research and scientific papers
Peculiarities of the tandem reaction between cyanoacetylenic alcohols and aminobenzoic acids: Synthesis of 5,5-dialkyl-2-(3-aminophenyl)-4-oxo-4,5- dihydrofuran-3-carbonitriles
Shemyakina, Olesya A.,Mal'kina, Anastasiya G.,Nosyreva, Valentina V.,Ushakov, Igor A.,Trofimov, Boris A.
, p. 319 - 325 (2012/11/07)
Tertiary cyanoacetylenic alcohols 1 reacting with 3-aminobenzoic acid (Et3N, MeCN, 20-25 °C, 28-30 h) afforded 5,5-dialkyl-2-(3- aminophenyl)-4-oxo-4,5-dihydrofuran-3-carbonitriles 2 (77-85%). Under the same condition, 4-hydroxy-4-methylpent-2-
Reactions of aminobenzoic acids with α,β-acetylenic γ-hydroxy nitriles: synthesis of functionalized amino acids and unusually facile esterification and acetylene hydration
Trofimov, Boris A.,Mal'kina, Anastasiya G.,Shemyakina, Olesya A.,Nosyreva, Valentina V.,Borisova, Angela P.,Albanov, Alexander I.,Kazheva, Olga N.,Alexandrov, Grigorii G.,Chekhlov, Anatolii N.,Dyachenko, Oleg A.
experimental part, p. 2472 - 2477 (2009/08/08)
2-Aminobenzoic acid 1 reacts with α,β-acetylenic γ-hydroxy nitriles 4 and 5 to afford 2-[(5-iminio-2,2-dialkyl-2,5-dihydro-3-furanyl)amino]benzenecarboxylates 7 and 8 (yield 73-74%), a new class of unnatural amino acids in a peculiar zwitterionic form, ha
