114622-14-9

Basic information

• Product Name: 6-Oxa-15,20,24,27-tetraazatetracyclo[13.9.6.22,5.17,11]tritriaconta-2,4,7,9,11(31),12,32-heptaene-14,26-dione,8-hydroxy-, (1S,12Z)- (9CI)
• Synonyms: 6-Oxa-15,20,24,27-tetraazatetracyclo[13.9.6.22,5.17,11]tritriaconta-2,4,7,9,11(31),12,32-heptaene-14,26-dione,8-hydroxy-, [S-(Z)]-; (+)-Chaenorpine; Chaenorpine
• CAS NO: 114622-14-9
• Molecular Formula: C28H36 N4 O4
• Molecular Weight: 492.618
• Mol File: 114622-14-9.mol

Chemical Properties

• CAS DataBase Reference: 6-Oxa-15,20,24,27-tetraazatetracyclo[13.9.6.22,5.17,11]tritriaconta-2,4,7,9,11(31),12,32-heptaene-14,26-dione,8-hydroxy-, (1S,12Z)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Oxa-15,20,24,27-tetraazatetracyclo[13.9.6.22,5.17,11]tritriaconta-2,4,7,9,11(31),12,32-heptaene-14,26-dione,8-hydroxy-, (1S,12Z)- (9CI)(114622-14-9)
• EPA Substance Registry System: 6-Oxa-15,20,24,27-tetraazatetracyclo[13.9.6.22,5.17,11]tritriaconta-2,4,7,9,11(31),12,32-heptaene-14,26-dione,8-hydroxy-, (1S,12Z)- (9CI)(114622-14-9)

Safety Data

• Hazardous Substances Data: 114622-14-9(Hazardous Substances Data)

Upstream product

• 312908-82-0 (-)-(8S)-1-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-8-(4-hydroxyphenyl)-1,5,9,13-tetraazacycloheptadecan-6-one 

Relevant articles and documents

Biomimetic formation of macrocyclic spermine alkaloids

Dihydroxyverbacine (10), a precursor for oxidative phenol coupling, was obtained via (±)-buchnerine (14), whose synthesis is described. The oxidizing system hemin (ferriprotoporphyrin IX chloride)/H2O2 promoted intramolecular coupling of 10 to give the alkaloids aphelandrine (1), orantine (2), and chaenorpine (7). The alkaloids were identified by on-line coupled HPLC and atmospheric-pressure chemical-ionization (APCI) mass spectrometry.