1146309-83-2Relevant academic research and scientific papers
Synthesis and biochemical properties of oligodeoxynucleotides acylated by the chemically stable 2-(trimethylsilyl)benzoyl (TMSBz) group at the 5′ or 3′ terminus
Yamada, Ken,Taguchi, Haruhiko,Ohkubo, Akihiro,Seio, Kohji,Sekine, Mitsuo
scheme or table, p. 5173 - 5176 (2010/11/16)
Oligodeoxynucleotides acylated with a 2-(trimethylsilyl)benzoyl (TMSBz) group at the 5′ or 3′ terminus were synthesized according to the general method used for DNA synthesis. The acylated DNA oligomers could be easily purified due to the high lipophilicity of the TMSBz group and showed enhanced hybridization ability and resistance to exonucleases.
