1146320-24-2Relevant academic research and scientific papers
Synthesis of new dipyrrolo- and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1-5, GSK-3) inhibitors
Rochais, Christophe,Duc, Nghia Vu,Lescot, Elodie,Sopkova-de Oliveira Santos, Jana,Bureau, Ronan,Meijer, Laurent,Dallemagne, Patrick,Rault, Sylvain
experimental part, p. 708 - 716 (2009/09/05)
We herein describe the synthesis of novel dipyrrolo- and furopyrrolopyrazinones related to highly cytotoxic tripentones and to their oximes. The synthetic pathway involved in particular a Curtius rearrangement and a subsequent cyclisation into the title p
