114636-48-5Relevant academic research and scientific papers
SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS
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Page/Page column 184, (2009/04/25)
Provided herein are spirocyclic aminoquinolones of formula I and compositions containing the compounds. The compounds and compositions provided herein are useful in the prevention, amelioration or treatment of GSK- 3 inhibitors mediated diseases. In Formu
Synthesis and bacterial DNA gyrase inhibitory properties of a spirocyclopropylquinolone derivative
Wentland,Perni,Dorff,Rake
, p. 1694 - 1697 (2007/10/02)
A novel conformationally restricted 1-cyclopropylquinolone (1) that incorporates structural features of both ofloxacin and ciprofloxacin has been prepared. Compound 1 was found to be a DNA gyrase inhibitor having potency similar to ofloxacin but less than
