1146362-41-5

Upstream product

• 459-22-3 4-fluorophenylacetonitrile 
• 55-51-6 N,N-bis(2-chloro-ethyl)-benzenemethanamine 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 192069-85-5 1-benzyl-4-(4-fluorophenyl)piperidine-4-carbonitrile 

Downstream Products

• 1146362-43-7 (4-fluorophenyl)-[4-(4-fluorophenyl)-piperidin-4-yl]methanone hydrochloride 

Relevant academic research and scientific papers

Rodent selectivity of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists: Insights from a receptor model

Rodent selectivity data of piperidine-4-yl-1H-indoles, a series of CC chemokine receptor-3 (CCR3) antagonists, are presented and discussed as part of an overall optimization effort within this lead compound class. Although attachment of an acidic moiety t

SUBSTITUTED PIPERAZINO-DIHYDROTHIENOPYRIMIDINES

The invention relates to new piperidino-dihydrothienopyrimidines of formula 1, as well as pharmacologically acceptable salts thereof, wherein X is SO or SO2, but preferably SO, and wherein R1, R2, R3 and R4 may have the meanings given in claim 1, as well as pharmaceutical compositions which contain these compounds. These new piperidino-dihydrothienopyrimidines are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin or eyes, diseases of the peripheral or central nervous system or cancers.