1146401-69-5Relevant academic research and scientific papers
4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production
Mitchell, Lorna,Wang, Zhi,Hu, Lain-Yen,Kostlan, Catherine,Carroll, Matthew,Dettling, Danielle,Du, Daniel,Pocalyko, David,Wade, Kimberly
experimental part, p. 1310 - 1313 (2009/11/30)
The first examples of thioether-substituted benzonitriles as potential soft-drug androgen receptor antagonists are reported. A number of 4-(alkylthio)- and of 4-(arylthio)-benzonitrile analogs were evaluated in human androgen receptor binding and cellular
