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1146413-10-6

4-(2-chloro-3-nitrophenyl)morpholine is an organic compound characterized by its chemical structure, which features a morpholine ring attached to a 2-chloro-3-nitrophenyl group. 4-(2-chloro-3-nitrophenyl)morpholine is a derivative of morpholine, a heterocyclic amine with the formula C4H8NO2, and the 2-chloro-3-nitrophenyl group introduces a chlorine atom at the 2nd position and a nitro group at the 3rd position of the phenyl ring. The combination of these functional groups gives 4-(2-chloro-3-nitrophenyl)morpholine unique chemical properties, making it potentially useful in various applications such as pharmaceuticals, agrochemicals, or as an intermediate in the synthesis of other organic compounds. Its specific reactivity, solubility, and stability can be influenced by the presence of the chlorine and nitro groups, which may also affect its potential applications and handling requirements.

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  • 1146413-10-6 Structure

  • Basic information

    1. Product Name: 4-(2-chloro-3-nitrophenyl)morpholine
    2. Synonyms: 4-(2-chloro-3-nitrophenyl)morpholine
    3. CAS NO:1146413-10-6
    4. Molecular Formula:
    5. Molecular Weight: 242.662
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1146413-10-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(2-chloro-3-nitrophenyl)morpholine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(2-chloro-3-nitrophenyl)morpholine(1146413-10-6)
    11. EPA Substance Registry System: 4-(2-chloro-3-nitrophenyl)morpholine(1146413-10-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1146413-10-6(Hazardous Substances Data)

1146413-10-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1146413-10-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,6,4,1 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1146413-10:
(9*1)+(8*1)+(7*4)+(6*6)+(5*4)+(4*1)+(3*3)+(2*1)+(1*0)=116
116 % 10 = 6
So 1146413-10-6 is a valid CAS Registry Number.

1146413-10-6Relevant articles and documents

TYK2 INHIBITORS AND USES THEREOF

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Paragraph 1441; 1442; 1443, (2019/02/13)

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

4-BENZ0YL-1-SUBSTITUTED-PIPERAZIN-2-0NE DERIVATIVES AS P2X7 MODULATORS

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Page/Page column 89, (2009/05/28)

The invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein: A is C1-6alkyl, C3-6cycloalkyl, -CH2-R6, -CHMe-R7, -CMe2-R7, or optionally substituted aryl; wherein, when A is optionally substituted aryl, said aryl group is optionally substituted with 1 to 3 substituents, which may be the same or different, selected from the group consisting of halogen, C1-6alkyl, -CF3, C1-4alkoxy, C1fluoroalkoxy, cyano, NR8R9; and pyridyl wherein the pyridyl is optionally substituted by one methyl; R1 is chlorine, fluorine, -CF3, cyano or C1-6alkyl; R2, R3 and R5 independently are hydrogen, fluorine, chlorine, -CF3, cyano or C1-6alkyl, such that at least one of R2, R3 and R5 is other than hydrogen; R4 is hydrogen. These compounds and salts are thought to be P2X7 receptor antagonists. The invention also provides the use of the compound or salt for the manufacture of a medicament for the treatment of pain, inflammation, rheumatoid arthritis, osteoarthritis, or a neurodegenerative disease.

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