114642-85-2Relevant academic research and scientific papers
Elimination from Diastereomeric Methyl 3-Acetoxy-2-halogeno- and 2,3-Dihalogeno-3-phenylpropanoates
Cabaleiro, Mercedes C.,Garay, Raul O.
, p. 1473 - 1476 (2007/10/02)
The rates of elimination of a number of erythro- and threo-PhCHYCXHCO2Me in methanolic triethylamine have been measured.The kinetic evidence together with the stereochemical results suggest that elimination of the dihalogeno-compounds occurs by an (E1cB)I process for the erythro-substrates and by a concerted pathways for the threo-isomers.In the case of the acetoxy derivatives the former mechanism seems to be operative for both stereoisomers.
