1146547-69-4Relevant academic research and scientific papers
Synthesis of carbolines by photostimulated cyclization of anilinohalopyridines
Laha, Joydev K.,Barolo, Silvia M.,Rossi, Roberto A.,Cuny, Gregory D.
experimental part, p. 6421 - 6425 (2011/09/15)
A general synthetic route to prepare all four carboline regioisomers by photostimulated cyclization of anilinohalopyridines is described. The methodology affords various substituted carbolines in good to excellent yields. In the case of α-carbolines, the SRN1 methodology complements previously reported palladium-catalyzed cyclization approaches.
One-pot synthesis of α-carbolines via sequential palladium-catalyzed aryl amination and intramolecular arylation
Laha, Joydev K.,Petrou, Philip,Cuny, Gregory D.
supporting information; experimental part, p. 3152 - 3155 (2009/08/07)
A one-pot synthesis of α-carbolines via a palladium-catalyzed aryl amination followed by intramolecular arylation is described. 2,3-Dichloro- and 2,3-dibromopyridines have been shown to react with readily available anilines to obtain various substituted α-carbolines in moderate to excellent yields.
