114671-18-0

Upstream product

• 139932-46-0 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid 4-[2-(phenoxycarbonylmethyl-carbamoyl)-1-trimethylsilanyl-ethyl]-benzyl ester 
• 1866-39-3 trans-p-methylcinnamic acid 
• 20754-20-5 3-p-tolyl-acrylic acid methyl ester 
• 104-87-0 4-methyl-benzaldehyde 
• 114671-13-5 methyl 3-(4'-methyl)phenyl-3-trimethylsilylpropanoate 
• 114671-15-7 3-<(4'-hydroxymethyl)phenyl>-3-trimethylsilylpropanoic acid 
• 139932-41-5 methyl 3-<(4'-bromomethyl)phenyl>-3-trimethylsilylpropanoate 
• 114671-14-6 methyl 3-<(4'-acetoxymethyl)phenyl>-3-trimethylsilylpropanoate 
• 114671-19-1 phenyl 3-<(4'-hydroxymethyl)phenyl>-3-trimethylsilylpropanoylglycinate 
• 139932-46-0 phenyl 3-<(4'-N^α-9-fluorenylmethoxycarbonylleucyloxymethyl)-phenyl>-3-trimethylsilylpropanoylglycinate 
• 35661-60-0 Fmoc-Leu-OH 

Downstream Products

• 139932-47-1 phenyl 3-<(2',2'-bis(4-nitrophenyl)ethoxycarbonyl)-glycyloxymethyl>-phenyl-3-trimethylsilylpropanoylglycinate 
• 114671-20-4 N^α-diphenylphosphinylleucylvalylglycylphenylalanylalanylleucine 
• 139932-48-2 3-<(2',2'-bis(4-nitrophenyl)ethoxycarbonyl)-glycyloxymethyl>-phenyl-3-trimethylsilylpropanoylglycine 

Relevant academic research and scientific papers

Solid phase peptide synthesis: Fluoride ion release of protected peptide fragments

A linker unit for solid phase peptide synthesis has been designed on the basis of organosilicon chemistry which allows efficient release, by fluoride ion nucleophilic attack at Si, of t-butyl-derived protected peptide fragments. Such protected fragments w

SOLID PHASE PEPTIDE SYNTHESIS: FLUORIDE ION RELEASE OF PEPTIDE FROM THE RESIN

A linkage to anchor the growing peptide chain has been designed in order to allow swift release of the peptide product by Bu4N(1+)*F(1-).Preparation of the linker (4) is described.