1146732-16-2Relevant academic research and scientific papers
Synthesis of nonsymmetrical 5-Aryl-2-indolopyrrole derivatives via controlled mono Suzuki-Miyaura cross-coupling on N-Boc-2,5-dibromopyrrole
Beaumard, Floriane,Dauban, Philippe,Dodd, Robert H.
experimental part, p. 4033 - 4042 (2011/02/22)
The first example of mono Suzuki-Miyaura cross-coupling of N-Boc-2,5-dibromopyrrole with a boronic acid (indol-2-ylboronic acid) is reported. The resulting 2-indolyl-5-bromopyrrole derivative was in turn coupled with a variety of aryl- or heteroarylboronic acids thereby providing the corresponding non-symmetrical 2,5-disubstituted pyrroles in good to excellent yields. The tert-butoxycarbonyl (Boc) groups could be easily removed to give the completely deprotected products. Georg Thieme Verlag Stuttgart - New York.
One-pot double suzuki- miyaura couplings: Rapid access to nonsymmetrical tri(hetero)aryl derivatives
Beaumard, Floriane,Dauban, Philippe,Dodd, Robert H.
supporting information; experimental part, p. 1801 - 1804 (2009/08/15)
We describe a one-pot, simultaneous Suzuki- Miyaura cross-coupling of two different aryl boronic acids with symmetrical dibromo aryl and heterocyclic substrates to give as major products the unsymmetrical disubstituted tri(hetero)aryl derivatives. Yields
