1146953-52-7

Upstream product

• 1146953-48-1 4-hydrazino-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 122-51-0 orthoformic acid triethyl ester 

Relevant academic research and scientific papers

Synthesis of pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidines

Starting from 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones, a synthesis pathway to the tricyclic pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidines is described. Reaction of 1,5-dihydro-4H-pyrazolo[3,4-d] pyrimidin-4-ones with phosphoryl chloride afforded

H2SO4/Silica gel: An efficient and reusable heterogeneous catalyst for the synthesis of pyrazolo[4,3-e][1,2,4]triazolo[4,3- c]pyrimidines

Sulfuric acid adsorbed on silica gel has been used as an effective and reusable catalyst for the synthesis of pyrazolo[4,3-e][1,2,4]triazolo-[4,3-c] pyrimidines through cyclocondensation of 4-hydrazino-1Hpyrazolo[3,4-d] pyrimidines with triethylorthoesters under conventional heating and solvent-free microwave irradiation conditions. The present methodology offers several advantages, such as high yields, short reaction times, mild reaction condition and a recyclable and relatively green catalyst with easy work up.