1146968-91-3Relevant articles and documents
Fluorinated isatin derivatives. Part 1: Synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors
Podichetty, Anil Kumar,Faust, Andreas,Kopka, Klaus,Wagner, Stefan,Schober, Otmar,Schaefers, Michael,Haufe, Guenter
experimental part, p. 2680 - 2688 (2009/08/15)
A series of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin derivatives has been synthesized and tested as inhibitors of caspases-3 and -7, which are known to be downstream enzymes critical in the execution of apoptosis. N-Propyl-