1146971-36-9Relevant academic research and scientific papers
Synthesis and antimalarial activity of hydroxyethylpiperazine derivatives
Cunico, Wilson,Gomes, Claudia R.B.,Moreth, Marcele,Manhanini, Diogo P.,Figueiredo, Isabela H.,Penido, Carmen,Henriques, Maria G.M.O.,Varotti, Fernando P.,Krettli, Antoniana U.
experimental part, p. 1363 - 1368 (2009/09/27)
The antimalarial activity of hydroxyethylpiperazine derivatives, synthesized from the reaction of (2S,3S)Boc-phenylalanine epoxide with benzylpiperazines in good yields (76-96%), has been evaluated in vitro against the Plasmodium falciparum W2 clone (chlo
Synthesis, antimalarial evaluation and molecular modeling studies of hydroxyethylpiperazines, potential aspartyl protease inhibitors, Part 2
Cunico, Wilson,Gomes, Claudia R.B.,Facchinetti, Victor,Moreth, Marcele,Penido, Carmen,Henriques, Maria G.M.O.,Varotti, Fernando P.,Krettli, Luisa G.,Krettli, Antoniana U.,da Silva, Franklin S.,Caffarena, Ernesto R.,de Magalhaes, Camila S.
scheme or table, p. 3816 - 3820 (2009/12/09)
The antimalarial acitivity of hydroxyethylamines, synthesized from the reaction of intermediated hydroxyethypiperazines with benzenesulfonyl chlorides or benzoyl chlorides, has been evaluated in vitro against a W2 Plasmodium falciparum clone. Some of the
