1147093-18-2Relevant academic research and scientific papers
Discovery and structure-activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers
Zhang, Han-Zhong,Crogan-Grundy, Candace,May, Chris,Drewe, John,Tseng, Ben,Cai, Sui Xiong
experimental part, p. 2852 - 2858 (2009/09/27)
1-(2-(2,5-Dimethoxyphenylthio)benzylidene)semicarbazide (2a) was discovered as a potent apoptosis inducer through our cell based HTS assay. SAR study led to the discovery of a more aqueous soluble analog (2-(2,5-dimethoxyphenylthio)-6-methoxybenzylideneam
