1147095-15-5

Basic information

• Product Name: 4-(hydroxymethyl)-3-(trifluoromethyl)phenol
• Synonyms: 4-(hydroxymethyl)-3-(trifluoromethyl)phenol
• CAS NO: 1147095-15-5
• Molecular Weight: 192.138
• Mol File: 1147095-15-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(hydroxymethyl)-3-(trifluoromethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(hydroxymethyl)-3-(trifluoromethyl)phenol(1147095-15-5)
• EPA Substance Registry System: 4-(hydroxymethyl)-3-(trifluoromethyl)phenol(1147095-15-5)

Safety Data

• Hazardous Substances Data: 1147095-15-5(Hazardous Substances Data)

Upstream product

• 320-32-1 4-hydroxy-2-(trifluoromethyl)benzoic acid 

Downstream Products

• 1253188-22-5 (4-(benzyloxy)-2-(trifluoromethyl)phenyl)methanol 

Relevant articles and documents

Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles

The Ca2+ release-activated Ca2+ (CRAC) channels control many Ca2+-modulated physiological processes in mammals. Hyperactivating CRAC channels are known to cause several human diseases, including Stormorken syndrome. Here, we show the design of azopyrazole-derived photoswitchable CRAC channel inhibitors (designated piCRACs), which enable optical inhibition of store-operated Ca2+ influx and downstream signaling. Moreover, piCRAC-1 has been applied in vivo to alleviate thrombocytopenia and hemorrhage in a zebrafish model of Stormorken syndrome in a light-dependent manner.