1147112-66-0 Usage
Description
1-Piperidinecarboxylic acid, 3-fluoro-4-hydroxy-, phenylmethyl ester, (3R,4S)is a specific chemical compound characterized by its molecular formula C13H17FNO3. It is a phenylmethyl ester of 3-fluoro-4-hydroxy-1-piperidinecarboxylic acid, featuring a stereochemistry of 3R,4S. 1-Piperidinecarboxylic acid, 3-fluoro-4-hydroxy-, phenylmethyl ester, (3R,4S)is utilized in various research and pharmaceutical applications, with a focus on the development of innovative medications and drugs. Its potential effects on the central nervous system are of particular interest, and it is currently under investigation for its therapeutic properties. The precise mechanism of action and potential applications of this compound remain subjects of ongoing study and research.
Uses
Used in Pharmaceutical Research and Development:
1-Piperidinecarboxylic acid, 3-fluoro-4-hydroxy-, phenylmethyl ester, (3R,4S)is employed as a key intermediate in the synthesis of new medications and drugs. Its unique structure and properties make it a valuable component in the development of novel therapeutic agents.
Used in Central Nervous System Research:
1-Piperidinecarboxylic acid, 3-fluoro-4-hydroxy-, phenylmethyl ester, (3R,4S)is used as a research tool to investigate its potential effects on the central nervous system. Its interaction with various neurological pathways and receptors is being studied to understand its therapeutic potential in treating neurological disorders.
Used in Drug Design and Medicinal Chemistry:
1-Piperidinecarboxylic acid, 3-fluoro-4-hydroxy-, phenylmethyl ester, (3R,4S)serves as a structural template for designing new drugs with improved pharmacological properties. Its unique stereochemistry and functional groups provide a foundation for the development of drugs with enhanced efficacy and selectivity.
Used in Neurodegenerative Disease Treatment:
1-Piperidinecarboxylic acid, 3-fluoro-4-hydroxy-, phenylmethyl ester, (3R,4S)is being investigated for its potential therapeutic properties in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Its effects on the central nervous system and its ability to modulate specific neurological pathways make it a promising candidate for further research and development in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 1147112-66-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,7,1,1 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1147112-66:
(9*1)+(8*1)+(7*4)+(6*7)+(5*1)+(4*1)+(3*2)+(2*6)+(1*6)=120
120 % 10 = 0
So 1147112-66-0 is a valid CAS Registry Number.
1147112-66-0Relevant articles and documents
HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR
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, (2018/07/29)
The present invention is directed to heteroarylpiperidine ether compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.
6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRIDIN-5-ONE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR
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Paragraph 0198, (2017/07/14)
The present invention is directed to 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-5-one compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.
IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS
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Page/Page column 16, (2010/04/27)
Compounds of Formula I and II: I II having the chemical names cis-6-fluoro-8-(3-fluoropiperidin-4-yloxy)-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinoline and 6-fluoro-8-(trans-3-fluoropiperidin-4-yloxy)-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinoline, respectively, and enantiomers and pharmaceutically acceptable salts thereof, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. The compounds of this invention have also been found to be inhibitors of Pim-1.
