1147422-00-1

Basic information

• Product Name: Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
• Synonyms: Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester;1-Boc-1H-octahydropyrrolo[3,2-c]pyridine;1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, octahydro-, 1,1-diMethylethyl ester;tert-butyl 2,3,3a,4,5,6,7,7a-octahydropyrrolo[3,2-c]pyridine-1-carboxylate
• CAS NO: 1147422-00-1
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 226.31528
• Mol File: 1147422-00-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester(1147422-00-1)
• EPA Substance Registry System: Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester(1147422-00-1)

Safety Data

• Hazardous Substances Data: 1147422-00-1(Hazardous Substances Data)

Usage

General Description

Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester is a chemical compound with the molecular formula C11H21NO2. It is commonly used as an intermediate in the synthesis of pharmaceutical compounds and organic chemicals. Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester is a tert-butyl ester derivative of octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid, which is a bicyclic heteroaromatic compound. It is often utilized in the development of potential drug candidates and as a building block in organic synthesis. Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester has various applications in pharmaceutical, chemical, and research industries due to its versatile reactivity and structural properties.

Upstream product

• 271-34-1 5-azaindole 
• 148760-75-2 tert-butyl 1H-pyrrolo[3,2-c]pyridine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1147421-99-5 5-benzyl-octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1438081-22-1 tert-butyl 5-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate 
• 1438072-89-9 N-(3-chloro-4-fluorophenyl)-6-(3-(hexahydro-1H-pyrrolo[3,2-c]pyridin-5(6H)-yl)propoxy)-7-methoxyquinazolin-4-amine 
• 1312784-24-9 benzyl 1-methylhexahydro-1H-pyrrolo[3,2-c]pyridine-5(6H)-carboxylate 
• 1312784-23-8 benzyl hexahydro-1H-pyrrolo[3,2-c]pyridine-5(6H)-carboxylate hydrochloride 
• 1312784-22-7 5-benzyl 1-tert-butyl hexahydro-1H-pyrrolo[3,2-c]pyridine-1,5(6H)-dicarboxylate 

Relevant articles and documents

AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE

The present invention relates to the field of medicine. Provided herein are aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in modulating the protein tyrosine kinase activity, and in modulating inter- and/or intra-cellular signaling. Also provided herein are pharmaceutically acceptable compositions comprising the aminoquinazoline compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

THIENOPYRIMIDIENE DERIVATIVES AS PI3K INHIBITORS

Thienopyrimidines of formula (I) wherein W and R1 to R4 are as defined in the claims, and the pharmaceutically acceptable salts thereof are inhibitors of PI3K and are selective for the p110δ isoform, which is a class Ia PI3 kinase, over both other class Ia and class Ib kinases. The compounds may be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.