1147422-28-3 Usage
Uses
Used in Pharmaceutical Industry:
4-(3-Fluoro-azetidin-1-yl)-piperidine serves as a key building block for the synthesis of a variety of compounds with targeted biological activities. Its unique structure allows for the development of new pharmaceuticals with specific therapeutic effects.
Used in Chemical Research:
In the realm of chemical research, 4-(3-Fluoro-azetidin-1-yl)-piperidine is utilized for studying the properties of heterocyclic compounds, including their stability and reactivity. This understanding can lead to advancements in the design of novel chemical entities with improved pharmacological profiles.
Used in Drug Discovery:
4-(3-Fluoro-azetidin-1-yl)-piperidine is employed in drug discovery processes to identify and optimize lead compounds with potential therapeutic applications. Its distinctive molecular structure aids in the exploration of new chemical spaces and the generation of innovative drug candidates.
Used in Medicinal Chemistry:
In medicinal chemistry, 4-(3-Fluoro-azetidin-1-yl)-piperidine is applied as a structural motif for the design of bioactive molecules. Its incorporation into drug molecules can modulate pharmacokinetic and pharmacodynamic properties, enhancing drug efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 1147422-28-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,7,4,2 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1147422-28:
(9*1)+(8*1)+(7*4)+(6*7)+(5*4)+(4*2)+(3*2)+(2*2)+(1*8)=133
133 % 10 = 3
So 1147422-28-3 is a valid CAS Registry Number.
1147422-28-3Relevant articles and documents
THIENOPYRIMIDIENE DERIVATIVES AS PI3K INHIBITORS
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Page/Page column 93, (2009/05/28)
Thienopyrimidines of formula (I) wherein W and R1 to R4 are as defined in the claims, and the pharmaceutically acceptable salts thereof are inhibitors of PI3K and are selective for the p110δ isoform, which is a class Ia PI3 kinase, over both other class Ia and class Ib kinases. The compounds may be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
PURINE DERIVATIVES USEFUL AS PI3 KINASE INHIBITORS
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Page/Page column 68, (2009/05/28)
This invention provides a compound which is a purine of formula (Ia) or (Ib): and the pharmaceutically acceptable salts thereof that are inhibitors of PI3K and a selective for the p110δ isoform, which is a class Ia PI3 kinase, over other class Ia PI3 kinases and over class Ib kinases. The compounds may be used to treat diseases and disorders arisi from abnormal cell growth, function or behaviour associated with PI3 kinase such as cance immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
