1147531-71-2

Upstream product

• 910486-28-1 4-(2,2,2-trifluoro-1,1-dimethylethyl)phenyl trifluoromethanesulfonate 
• 13939-06-5 molybdenum hexacarbonyl 
• 1225380-05-1 1-bromo-4-(1,1,1-trifluoro-2-methylpropan-2-yl)-benzene 
• 1418296-99-7 4-(1,1,1-trifluoro-2-methylpropan-2-yl)benzaldehyde 

Relevant academic research and scientific papers

Benzo Annulenes as Antiviral Agents

The present disclosure is concerned with benzo annulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, usi

BTK protein kinase inhibitors

This application discloses pyridine and pyrimidine compounds according to formula I wherein R1, R2, R3, R4, R5, X1 and A are as described herein which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of formula I and at least one carrier, diluent or excipient.