1147743-63-2Relevant articles and documents
Towards an efficient prodrug of the alkylating metabolite monomethyltriazene: Synthesis and stability of N-acylamino acid derivatives of triazenes
Perry, Maria de Jesus,Carvalho, Emilia,Rosa, Eduarda,Iley, Jim
experimental part, p. 1049 - 1056 (2009/08/14)
A series of 3-[α-(acylamino)acyl]-1-aryl-3-methyltriazenes 6a-l, potential cytotoxic triazene prodrugs, were synthesised by coupling 1-aryl-3-methyltriazenes to N-acylamino acids. Their hydrolysis was studied in isotonic pH 7.4 phosphate buffer and in hum