1147846-00-1

Basic information

• Product Name: N,N-diisopropyl-3-(4-(trifluoromethyl)phenyl)prop-2-yn-1-amine
• Synonyms: N,N-diisopropyl-3-(4-(trifluoromethyl)phenyl)prop-2-yn-1-amine
• CAS NO: 1147846-00-1
• Molecular Weight: 283.337
• Mol File: 1147846-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-diisopropyl-3-(4-(trifluoromethyl)phenyl)prop-2-yn-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diisopropyl-3-(4-(trifluoromethyl)phenyl)prop-2-yn-1-amine(1147846-00-1)
• EPA Substance Registry System: N,N-diisopropyl-3-(4-(trifluoromethyl)phenyl)prop-2-yn-1-amine(1147846-00-1)

Safety Data

• Hazardous Substances Data: 1147846-00-1(Hazardous Substances Data)

Upstream product

• 10342-97-9 N,N-diisopropylmethylamine 

Downstream Products

• 1147846-04-5 (E)-[5-(tert-butyldimethylsilyl)-3-(4-trifluoromethylphenyl)-2-penten-4-ynyl]diisopropylamine 

Relevant articles and documents

A highly efficient gold-catalyzed photoredox α-C(sp3)-H alkynylation of tertiary aliphatic amines with sunlight

A new α-C(sp3)-H alkynylation of unactivated tertiary aliphatic amines with 1-iodoalkynes as radical alkynylating reagents in the presence of [Au2(μ-dppm)2]2+ in sunlight provides propargylic amines. Based on mechanistic studies, a C-C coupling of an α-aminoalkyl radical and an alkynyl radical is proposed for the C(sp3)-C(sp) bond formation. The mild, convenient, efficient, and highly selective C(sp3)-H alkynylation reaction shows excellent regioselectivity and good functional-group compatibility. A scale-up to gram quantities is possible with sunlight used as a clean and sustainable energy source.