1147998-27-3

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)-;1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine;1-(benzenesulfonyl)-5-(1H-pyrazol-4-yl)pyrrolo[2,3-b]pyridine
• CAS NO: 1147998-27-3
• Molecular Formula: C₁₆H₁₂N₄O₂S
• Molecular Weight: 324.35708
• Mol File: 1147998-27-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)-(1147998-27-3)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 1-(phenylsulfonyl)-5-(1H-pyrazol-4-yl)-(1147998-27-3)

Safety Data

• Hazardous Substances Data: 1147998-27-3(Hazardous Substances Data)

Usage

Chemical Class

Pyrrolopyridine

Core Structure

Pyrrolopyridine

Substituents

Phenylsulfonyl group at the 1 position, Pyrazol-4-yl group at the 5 position

Potential Applications

Medicinal chemistry, pharmaceutical drug development

Use as Building Block

Organic synthesis, creation of diverse chemical structures

Biological Activity

Potential usefulness in research and development in pharmaceutical and biotechnology industries

Upstream product

• 552846-17-0 tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylate 
• 1001070-33-2 1-(benzenesulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1147998-28-4 tert-butyl 4-[1-(-phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-1H-pyrazole-1-carboxylate 

Relevant articles and documents

THERAPEUTIC COMPOUNDS

The present invention relates to pyrazine substituted pyrrolopyridines which are inhibitors of JAK kinases (JAKl, JAK2, JAK3 and/or TYK2) and/or PDKl and are thus useful for the treatment of myeloproliferative disorders or cancer.