1148026-98-5

Basic information

• Product Name: Bromo-PEG3-phosphonic acid ethyl ester
• Synonyms: Bromo-PEG3-phosphonic acid ethyl ester;Bromo-PEG9-phosphonic acid ethyl ester;Bromo-PEG3-phosphonic acid diethyl ester
• CAS NO: 1148026-98-5
• Molecular Formula: C12H26BrO6P
• Molecular Weight: 377.209001
• Mol File: 1148026-98-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Bromo-PEG3-phosphonic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Bromo-PEG3-phosphonic acid ethyl ester(1148026-98-5)
• EPA Substance Registry System: Bromo-PEG3-phosphonic acid ethyl ester(1148026-98-5)

Safety Data

• Hazardous Substances Data: 1148026-98-5(Hazardous Substances Data)

Usage

Description

Bromo-PEG3-phosphonic acid ethyl ester is a PEG linker that features a bromine atom and a hydrophilic PEG chain. The bromine atom, due to its size and electronegative properties, acts as an effective leaving group and can engage in substitution reactions. The hydrophilic PEG chain enhances the compound's solubility in aqueous environments, making it a versatile molecule for various applications.

Uses

Used in Chemical Synthesis:
Bromo-PEG3-phosphonic acid ethyl ester is used as a PEG linker for chemical synthesis, providing a hydrophilic and soluble platform that facilitates the attachment of various functional groups and molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Bromo-PEG3-phosphonic acid ethyl ester is used as a building block for the development of drugs with improved water solubility and bioavailability. The PEG linker can be utilized to enhance the pharmacokinetic properties of drug candidates, potentially leading to more effective therapies.
Used in Bioconjugation:
Bromo-PEG3-phosphonic acid ethyl ester is used as a bioconjugation agent to attach biologically active molecules, such as proteins, peptides, or nucleic acids, to PEG chains. This modification can improve the stability, solubility, and circulation time of these biomolecules in biological systems, which is crucial for their therapeutic or diagnostic applications.
Used in Material Science:
In material science, Bromo-PEG3-phosphonic acid ethyl ester is used as a component in the design of novel materials with tailored properties. The PEG linker can be incorporated into polymers, hydrogels, or other materials to introduce hydrophilicity, enhance solubility, or modify the material's interaction with biological systems.
Used in Diagnostics:
Bromo-PEG3-phosphonic acid ethyl ester is used as a modifier in the development of diagnostic tools, such as imaging agents or sensors. The PEG linker can improve the biocompatibility and solubility of these diagnostic agents, potentially enhancing their performance and reducing side effects.