1148026-99-6

Basic information

• Product Name: Bromo-PEG3-phosphonic acid
• Synonyms: Bromo-PEG3-phosphonic acid
• CAS NO: 1148026-99-6
• Molecular Formula: C8H18BrO6P
• Molecular Weight: 321.102681
• Mol File: 1148026-99-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 458.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.514±0.06 g/cm3(Predicted)
• PKA: 2.14±0.10(Predicted)
• CAS DataBase Reference: Bromo-PEG3-phosphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Bromo-PEG3-phosphonic acid(1148026-99-6)
• EPA Substance Registry System: Bromo-PEG3-phosphonic acid(1148026-99-6)

Safety Data

• Hazardous Substances Data: 1148026-99-6(Hazardous Substances Data)

Usage

Description

Bromo-PEG3-phosphonic acid is a PEG (polyethylene glycol) linker with bromine and phosphonic acid moieties attached to it. The bromine atom serves as a good leaving group, while the hydrophilic PEG chain enhances the compound's solubility in aqueous media. This unique structure makes it a versatile molecule with potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
Bromo-PEG3-phosphonic acid is used as a building block for the synthesis of various pharmaceutical compounds. The bromine atom can be easily replaced with other functional groups, allowing for the creation of a wide range of molecules with different properties and applications.
Used in Bioconjugation:
Bromo-PEG3-phosphonic acid is used as a bioconjugation agent for the attachment of biomolecules, such as proteins, peptides, and nucleic acids, to other molecules or surfaces. The phosphonic acid moiety can form stable covalent bonds with various functional groups, making it a useful tool for creating stable and functional bioconjugates.
Used in Drug Delivery Systems:
Bromo-PEG3-phosphonic acid is used as a component in the development of drug delivery systems, particularly for targeted drug delivery. The PEG chain can improve the solubility and bioavailability of drugs, while the bromine and phosphonic acid moieties can be used to attach targeting ligands or other functional groups to the drug delivery system.
Used in Chemical Synthesis:
Bromo-PEG3-phosphonic acid is used as an intermediate in the synthesis of various chemical compounds, including those with potential applications in materials science, pharmaceuticals, and other industries. The bromine atom can be replaced with a wide range of functional groups, making it a versatile building block for chemical synthesis.
Used in Surface Modification:
Bromo-PEG3-phosphonic acid is used for surface modification of materials, such as nanoparticles, to improve their stability, biocompatibility, and targeting capabilities. The phosphonic acid moiety can form strong bonds with metal surfaces, while the PEG chain can provide a hydrophilic and biocompatible coating.