1148044-27-2 Usage
Uses
Used in Organic Synthesis:
1-tert-butyl 2-Methyl 2-(2-oxoethyl)azetidine-1,2-dicarboxylate is used as a reagent in organic synthesis for its ability to form chemical bonds and participate in various reactions. Its unique structure allows it to be a versatile component in the creation of new organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-tert-butyl 2-Methyl 2-(2-oxoethyl)azetidine-1,2-dicarboxylate is used as a research compound to explore its potential medicinal properties. Its complex structure and reactivity make it a candidate for the development of new drugs, particularly in the context of its ability to engage in chemical bonding and reactions that could lead to therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1148044-27-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,8,0,4 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1148044-27:
(9*1)+(8*1)+(7*4)+(6*8)+(5*0)+(4*4)+(3*4)+(2*2)+(1*7)=132
132 % 10 = 2
So 1148044-27-2 is a valid CAS Registry Number.
1148044-27-2Relevant academic research and scientific papers
Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors
Sippy, Kevin B.,Anderson, David J.,Bunnelle, William H.,Hutchins, Charles W.,Schrimpf, Michael R.
scheme or table, p. 1682 - 1685 (2009/11/30)
Several N-pyridin-3-yl spirobicyclic diamines, designed as conformationally restricted analogs of tebanicline (ABT-594), were synthesized as novel ligands for nicotinic acetylcholine receptors (nAChR). The spirocyclic compounds exhibited weaker binding affinity, than other constrained analogs in accord with a pharmacophore model. Nevertheless, some (1a, 1b) possessed (partial) agonist potencies comparable to nicotine at the α4β2 subtype, but with greatly improved selectivity relative to the α3β4* nAChR.