1148044-28-3 Usage
Explanation
The full chemical name of the compound, which describes its structure and functional groups.
Explanation
The molecular formula represents the number of carbon (C), hydrogen (H), nitrogen (N), and oxygen (O) atoms in the compound.
Explanation
The molecular weight is the sum of the atomic weights of all the atoms in the molecule.
Explanation
These functional groups are present in the compound and contribute to its chemical properties and reactivity.
Explanation
The compound is derived from a spiro-alkaloid, which is a type of organic compound with a spiro-connected nitrogen-containing ring.
Explanation
The compound is primarily used as a building block in the synthesis of various pharmacologically active molecules, contributing to drug development.
Explanation
The presence of the 1,1-dimethylethyl ester group improves the solubility of the compound, making it more suitable for chemical reactions and drug development.
Explanation
The ester group also contributes to the stability of the compound, making it a more reliable building block for the synthesis of active pharmaceutical ingredients.
Explanation
The unique structure and properties of the compound make it a valuable candidate for research and development of new drugs with various therapeutic applications.
Explanation
The compound's unique structure and potential applications in drug development make it an important chemical for researchers to study and utilize in the creation of novel therapeutic agents.
Molecular Weight
299.38 g/mol
Functional Groups
Carboxylic acid, ester, amide, and aromatic ring
Structure
Spiro-alkaloid derivative
Application
Pharmaceutical intermediate
Solubility
Enhanced by the 1,1-dimethylethyl ester group
Stability
Improved by the 1,1-dimethylethyl ester group
Pharmacological Properties
Potential applications in the development of new drugs
Research Value
Valuable for research and drug development purposes
Check Digit Verification of cas no
The CAS Registry Mumber 1148044-28-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,8,0,4 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1148044-28:
(9*1)+(8*1)+(7*4)+(6*8)+(5*0)+(4*4)+(3*4)+(2*2)+(1*8)=133
133 % 10 = 3
So 1148044-28-3 is a valid CAS Registry Number.
1148044-28-3Relevant academic research and scientific papers
Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors
Sippy, Kevin B.,Anderson, David J.,Bunnelle, William H.,Hutchins, Charles W.,Schrimpf, Michael R.
scheme or table, p. 1682 - 1685 (2009/11/30)
Several N-pyridin-3-yl spirobicyclic diamines, designed as conformationally restricted analogs of tebanicline (ABT-594), were synthesized as novel ligands for nicotinic acetylcholine receptors (nAChR). The spirocyclic compounds exhibited weaker binding affinity, than other constrained analogs in accord with a pharmacophore model. Nevertheless, some (1a, 1b) possessed (partial) agonist potencies comparable to nicotine at the α4β2 subtype, but with greatly improved selectivity relative to the α3β4* nAChR.
