114873-00-6

Basic information

• Product Name: BOC-L-2-Fluorophe
• Synonyms: BOC-2-FLUORO-L-PHENYLALANINE;BOC-L-2-FLUOROPHE;BOC-L-2-FLUOROPHENYLALANINE;BOC-L-PHE(2-F)-OH;BOC-O-FLUORO-PHE-OH;BOC-PHE(O-F)-OH;BOC-PHE(2-F)-OH;BOC-(S)-2-AMINO-3-(2'-FLUOROPHENYL)PROPANOIC ACID
• CAS NO: 114873-00-6
• Molecular Formula: C₁₄H₁₈FNO₄
• Molecular Weight: 283.3
• EINECS: 220-105-7
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;chiral;Peptide;a-amino
• Mol File: 114873-00-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 92-96 °C
• Boiling Point: 427.3 °C at 760 mmHg
• Flash Point: 212.2 °C
• Appearance: white to light yellow crystal powder
• Density: 1.1918 (estimate)
• Vapor Pressure: 4.61E-08mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: Keep Cold
• PKA: 3.87±0.11(Predicted)
• BRN: 5347990
• CAS DataBase Reference: BOC-L-2-Fluorophe(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-L-2-Fluorophe(114873-00-6)
• EPA Substance Registry System: BOC-L-2-Fluorophe(114873-00-6)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 114873-00-6(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powde

InChI:InChI=1/C14H18FNO4/c1-14(2,3)20-13(19)16-11(12(17)18)8-9-6-4-5-7-10(9)15/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)/t11-/m1/s1

Upstream product

• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 19883-78-4 (S)-2-fluorophenylalanine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 174611-08-6 1S-1-(3,5-dibenzyloxycarbonylphenylaminocarbonyl)-2-(2-fluorophenyl)ethylamine 
• 141088-04-2 (4S,7S,10S)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(2-fluoro-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid 
• 119769-42-5 [(S)-1-{(R)-1-[({[(S)-1-Carbamoyl-2-(2-fluoro-phenyl)-ethyl]-ethyl-carbamoyl}-methyl)-carbamoyl]-4-guanidino-butylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 119745-15-2 ({[(S)-1-Carbamoyl-2-(2-fluoro-phenyl)-ethyl]-ethyl-carbamoyl}-methyl)-carbamic acid tert-butyl ester 
• 119744-80-8 (S)-2-Ethylamino-3-(2-fluoro-phenyl)-propionamide 

Relevant articles and documents

EPOXYSUCCINIC ACID DERIVATIVES

A compound of the general formula: STR1 wherein R 1 represents a carboxyl group which may optionally be esterified or amidated; R 2 represents a cyclic group which may optionally be substituted or a polar group; n is an integer of 0 to 6; R 3 represents hydrogen or a hydrocarbon residue which may optionally be substituted; R 4 represents (1) a hydrocarbon residue which is substituted by an optionally protected amino group or (2) an alkenyl group; or R 3 and R 4 may be combined with the adjacent nitrogen atom to form a heterocyclic group containing at least two hetero atoms, or a salt thereof.The compound or a salt thereof of the present invention inhibits thiol proteases such as cathepsin L and B and serves well as a prophylactic/therapeutic agent for bone diseases such as osteoporosis.

Amino acids and peptides. X. Leu-enkephalin analogues containing a fluorinated aromatic amino acid

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