114896-48-9

Upstream product

• 109-01-3 1-methyl-piperazine 
• 114896-46-7 2-(chloroacetyl)-1-phenyl-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole 
• 3790-45-2 1-phenyl-2,3,4,9-tetrahydro-1H-beta-carboline 
• 4753-09-7 N-benzoyltryptamine 
• 10022-79-4 1-phenyl-4,9-dihydro-3H-β-carboline 

Relevant academic research and scientific papers

1-METHYL-, 1-PHENYL, AND 1-(2-(2-DIMETHYLAMINOETHOXY)PHENYL)-2,3,4,9-TETRAHYDRO-1H-PYRIDOINDOLE AND THEIR 2-SUBSTITUTED DERIVATIVES: SYNTHESIS AND PHARMACOLOGICAL SCREENING

1-Methyl- and 1-phenyl-2,3,4,9-tetrahydro-1H-pyridoindole (I and IV) were transformed via the chloroacetyl derivatives II and V to the 4-methylpiperazinoacetyl compounds III and VI; compound VI inhibits effectively the formation of the indomethacin-induced gastric ulcers in rats but is devoid of anticholinergic activity and does not inhibit the gastric secretion in rats.Reaction of tryptamine with 2-(2-dimethylaminoethoxy)benzaldehyde afforded compound IX which proved inactive in tests for antidepressant activity.Compounds IV and IX were treated with ethyl chloroformate and gave carbamates VII and X; compound VII does not show anticonvulsant activity.