114912-36-6

Basic information

• Product Name: Ciwujianoside E
• Synonyms: Ciwujianoside E;(3beta)-3-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl]oxy]-30-noroleana-12,20(29)-dien-28-oic acid;Guaianin A
• CAS NO: 114912-36-6
• Molecular Formula: C₄₀H₆₂O₁₁
• Molecular Weight: 718.91368
• Mol File: 114912-36-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 824.4±65.0 °C(Predicted)
• Appearance: /
• Density: 1.30±0.1 g/cm3(Predicted)
• PKA: 4.51±0.70(Predicted)
• CAS DataBase Reference: Ciwujianoside E(CAS DataBase Reference)
• NIST Chemistry Reference: Ciwujianoside E(114912-36-6)
• EPA Substance Registry System: Ciwujianoside E(114912-36-6)

Safety Data

• Hazardous Substances Data: 114912-36-6(Hazardous Substances Data)

Usage

General Description

Ciwujianoside E is a natural compound found in the Ciwujia plant (Acanthopanax senticosus), which has been used in traditional Chinese medicine for its adaptogenic and antioxidant properties. This chemical has been studied for its potential pharmacological activities, including anti-inflammatory, anti-fatigue, and neuroprotective effects. Ciwujianoside E has also been investigated for its potential in treating diabetes and its protective effects on the cardiovascular system. It is believed to exert its effects through various mechanisms, such as modulating the activity of inflammatory mediators, regulating energy metabolism, and reducing oxidative stress. Overall, Ciwujianoside E has shown promising therapeutic potential and is an active area of research for its possible medicinal applications.

Upstream product

• 114892-56-7 ciwujianoside C₂ 

Downstream Products

• 5328-37-0 L-arabinose 
• 3615-41-6 L-Rhamnose 

Relevant articles and documents

Saponins from Leaves of Acanthopanax senticosus HARMS., Ciwujia; Structures of Ciwujianosides B, C1, C2, C3, C4, D1, D2 and E

Eleven triterpenoid saponins were isolated from the leaves of a Chinese folk medicine, Acanthopanax senticosus (RUPR. et MAXIM) HARMS.Of these compounds, three were identified as known saponins.The structures of eight new saponins named ciwujianosides B (1), C1, (2), C2 (3), C3 (4), C4 (5), D1 (6), D2 (7), and E (8) were elucidated to be as follows: (1), 3-O-α-rhamnopyranosyl-(1->2)-β-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (2), 3-O-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (3), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (4), 3-O-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl(1->6)-β-glucopyranosyl ester; (5), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (6), 3-O-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl(1->6)-β-glucopyranosyl ester; (7), 3-O-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-b-glucopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (8), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid.Keywords - Acanthopanax senticosus; Araliaceae; saponin; Chinese folk medicine; ciwujianoside; oleanolic acid glycoside; noroleanolic acid glycoside; 30-norolean-12,20(29)-dien-28-oic acid; ciwujia