114915-15-0

Basic information

• Product Name: N-Debenzoyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl}paclitaxel
• Synonyms: N-Debenzoyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl}paclitaxel;N-Debenzoyl-7-[[(2,2,2-trichloroethoxy)carbonyl]oxy]taxol
• CAS NO: 114915-15-0
• Molecular Formula: C₄₃H₄₈Cl₃NO₁₅
• Molecular Weight: 925.19792
• Product Categories: Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 114915-15-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Solubility: Ethyl Acetate, Methanol
• CAS DataBase Reference: N-Debenzoyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl}paclitaxel(CAS DataBase Reference)
• NIST Chemistry Reference: N-Debenzoyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl}paclitaxel(114915-15-0)
• EPA Substance Registry System: N-Debenzoyl-7-{[(2,2,2,-trichloroethyl)oxy]carbonyl}paclitaxel(114915-15-0)

Safety Data

• Hazardous Substances Data: 114915-15-0(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 114915-15-0 differently. You can refer to the following data:
1. A Paclitaxel (Taxol) derivative. It can be useful for the treatment of cancer. Antitumor agent. Paclitaxel - In House Impurity.
2. A Paclitaxel (Taxol)

Upstream product

• 114915-13-8 C₄₈H₅₆Cl₃NO₁₇ 
• 114915-24-1 7(2,2,2-trichloroethyloxycarbonyl)-13-cinnamoyl baccatin III_. 
• 140-10-3 (E)-3-phenylacrylic acid 
• 144704-63-2 (4S,5R)-3-((2S,3R)-2-Bromo-3-hydroxy-3-phenyl-propionyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 143527-74-6 ethyl (4S,5R)-3-tert-butoxycarbonyl-2,2-dimethyl-4-phenyl-5-oxazolidinecarboxylate 
• 143615-03-6 (4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid 
• 143527-75-7 (2R,3S) ethyl N-(t-butoxycarbonyl)-3-phenylisoserine 
• 126060-73-9 ethyl (2R,3R)-3-phenyl-2,3-oxiranepropanoate 
• 115437-18-8 7-triethylsilyl-10-deacetylbaccatin III 
• 100-52-7 benzaldehyde 
• 144787-20-2 (2R,3S)-3-azido-2-hydroxy-benzenepropanoic acid ethyl ester 
• 143615-00-3 (2R,3S)-3-amino-3-phenyl-2-hydroxypropionic acid ethyl ester 
• 32981-86-5 10-deacetylbaccatin III 
• 27548-93-2 baccatin III 

Downstream Products

• 33069-62-4 taxol 
• 1053611-06-5 C₆₀H₆₄N₂O₁₈ 
• 1054642-58-8 C₆₅H₆₆Cl₆N₂O₂₀ 
• 114915-17-2 C₅₀H₅₂Cl₃NO₁₆ 

Relevant articles and documents

Design and synthesis of a taxoid library using radiofrequency encoded combinatorial chemistry

Radiofrequency encoded combinatorial (REC) chemistry is a recently developed nonchemical encoding strategy in library synthesis. Encoded chemical libraries of complex molecular structures like Taxol can be constructed employing the noninvasive REC strategy and novel solid phase synthesis techniques, as demonstrated by the synthesis of the first 400- membered taxoid library in a discrete format and in quantities of multimilligrams/member.

Application of the vicinal oxyamination reaction with asymmetric induction to the hemisynthesis of taxol and analogues

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