114918-31-9Relevant articles and documents
Structure-activity relationship of quinazolinedione inhibitors of calcium-independent phosphodiesterase
Lowe III,Archer,Chapin,Cheng,Helweg,Johnson,Koe,Lebel,Moore,Nielsen,Russo,Shirley
, p. 624 - 628 (1991)
A series of quinazolinediones and azaquinazolinediones is described which possess potent inhibitory activity toward the calcium-independent phosphodiesterase enzyme (CaIPDE). In vivo testing showed that this in vitro activity translates to animal models p