114953-35-4

Upstream product

• 134368-38-0 diphenylmethyl 7β-amino-7α-formamido-3-[(1,3,4-thiadiazol-2-yl)thiomethyl]ceph-3-em-4-carboxylate 
• 7440-66-6 zinc 
• 86062-29-5 t-butyl 7α-formamido-7β-<(2,2,2-trichloroethoxy)carbonylamino>cephalosporanate 
• 86062-28-4 t-butyl 7α-(methylthio)-7β-<(2,2,2-trichloroethoxy)carbonylamino>cephalosporanate 
• 86064-51-9 t-butyl 7α-amino-7β-<(2,2,2-trichloroethoxy)carbonylamino>cephalosporanate 
• 86070-50-0 (6R,7R)-3-Acetoxymethyl-7-formylamino-8-oxo-7-(2,2,2-trichloro-ethoxycarbonylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 54820-94-9 t-butyl 7β-amino-7α-(methylthio)cephalosporanate 
• 86070-52-2 diphenylmethyl 7α-formamido-3-<(1-methyl-1H-tetrazol-5-yl)thiomethyl>-7β-<(2,2,2-trichloroethoxy)carbonylamino>ceph-3-em-4-carboxylate 
• 86070-51-1 (6R,7R)-7-Formylamino-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-7-(2,2,2-trichloro-ethoxycarbonylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 

Downstream Products

• 134368-39-1 Diphenylmethyl 7β-Amino-3-bromomethyl-7α-formamidoceph-3-em-4-carboxylate 

Relevant academic research and scientific papers

Cephalosporin derivatives

7 α-formamido cephalosporin derivatives having a 3[N-(optionally substituted)aminothiopyridinium thiomethyl] substituent have anti-bacterial activity and are of use in anti-bacterial therapy. Processes for the preparation thereof and intermediates for use in these processes are also disclosed.

Preparation and Properties of 7α-Formamido Cephalosporins

The preparation of novel antibacterially active 7α-formamido cephalosporins from the corresponding 7α-(methylthio) analogues by mercury(II)-mediated displacement with ammonia and subsequent formylation is described.The amine (2), a versatile intermediate,