114954-25-5Relevant articles and documents
New heteroaromatic aminations on 5-aryl-1,2,4-triazines and 1,2,4,5-tetrazines by palladium catalysis
Pellegatti, Laurent,Vedrenne, Emeline,Leger, Jean-Michel,Jarry, Christian,Routier, Sylvain
scheme or table, p. 4383 - 4389 (2010/07/05)
The efficient and original palladium-catalyzed amination of 5-Aryl-1,2,4-triazines and 1,2,4,5-tetrazines is reported. This Buchwald-Hartwig type reaction leads to the formation of aminated heterocycles via methylsulfur release. The reaction is optimized and a wide range of amines is used to determine the scope and limitations of this methodology.