114968-99-9Relevant academic research and scientific papers
A metal-free and regioselective approach to (Z)-β-fluorovinyl sulfones and their chemoselective hydrogenation to β-fluoroalkyl sulfones
Sedgwick, Daniel M.,Román, Raquel,Barrio, Pablo,Morales, Cristina,Fustero, Santos
, p. 108 - 116 (2018)
A highly regioselective, metal-free hydrofluorination reaction of alkynyl sulfones was developed using TBAF—one of the cheapest and most commonly available fluoride sources. In addition, the reactivity of the resulting β-fluorovinyl sulfones was studied, focusing on their selective hydrogenation reaction. Both β-fluorovinyl sulfones and their hydrogenation products β-fluoroalkyl sulfones may find applications in medicinal and agrochemical sciences.
Efficient nucleophilic fluoromethylation and subsequent transformation of alkyl and benzyl halides using fluorobis(phenylsulfonyl)methane
Prakash, G. K. Surya,Chacko, Sujith,Vaghoo, Habiba,Shao, Nan,Gurung, Laxman,Mathew, Thomas,Olah, George A.
supporting information; experimental part, p. 1127 - 1130 (2009/07/25)
An efficient methodology for the nucleophilic fluoromethylation of alkyl and benzyl halides using r-fluoro-α-(phenylsulfonyl)methane (1) as a highly versatile reagent is reported. Using benzyl halides, stereospecific one-pot synthesis of α-fluorovinyl com
DIETHYL 1-FLUORO-1-PHENYLSULFONYLMETHANEPHOSPHONATE, A VERSATILE AGENT FOR THE PREPARATION OF MONOFLUORINATED BUILDING BLOCKS
Koizumi, Toru,Hagi, Toru,Horie, Yoshiharu,Takeuchi, Yoshio
, p. 3959 - 3962 (2007/10/02)
Diethyl 1-fluoro-1-phenylsulfonylmethanephosphonate was prepared and was transformed into 1-fluoroalkanephosphonate and phenyl 1-fluorovinyl sulfones, which are useful monofluorinated building blocks.KEYWORDS - diethyl 1-fluoro-1-phenylsulfonylmethanephosphonate; 1-fluoroalkanephosphonate; 1-fluorovinyl sulfone; monofluorinated building block; cycloaddition; Michael reaction; Emmons-Horner reaction
