114988-00-0Relevant articles and documents
Novel DNA Analog for Potential Gene Regulating Agent. A Convenient Synthesis of α-Oligodeoxyribonucleotide Phosphorothioate Bearing 3'-Monophosphate
Shinozuka, Kazuo,Morita, Tsutomu,Hirota, Yoshiki,Sawai, Hiroaki
, p. 1941 - 1944 (1991)
α-2'-Deoxyoctathymydilic acid phosphorothioate analog bearing 3'-monophosphate was conveniently synthesized via phosphoramidite method using a riboadenosine attached Teflon-based solid support.The obtained oligomer exhibited enhanced stability toward the digestion by common nucleases.