114991-28-5

Basic information

• Product Name: HIV (GP120) FRAGMENT (315-329)
• Synonyms: GP120 (313-327);H-ARG-ILE-GLN-ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE-GLY-LYS-OH;HIV (GP120) FRAGMENT (315-329);ARG-ILE-GLN-ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE-GLY-LYS;R15K;HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22);HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22) HIV-1 env Protein gp120 (283-297) (strain BRU), P18IIIB;HIV-1 env Protein gp120 (283-297) (strain BRU), P18IIIB, HIV gp120 FragMent (315-329)
• CAS NO: 114991-28-5
• Molecular Formula: C73H126N26O18
• Molecular Weight: 1655.94
• Mol File: 114991-28-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: HIV (GP120) FRAGMENT (315-329)(CAS DataBase Reference)
• NIST Chemistry Reference: HIV (GP120) FRAGMENT (315-329)(114991-28-5)
• EPA Substance Registry System: HIV (GP120) FRAGMENT (315-329)(114991-28-5)

Safety Data

• Hazardous Substances Data: 114991-28-5(Hazardous Substances Data)

Usage

General Description

HIV (GP120) FRAGMENT (315-329) is a peptide fragment derived from the glycoprotein 120 (GP120) found in the human immunodeficiency virus (HIV). This fragment specifically encompasses amino acids 315 to 329 within the GP120 protein. GP120 is important for the virus' ability to bind to and enter host cells, so this fragment has been studied for its potential in developing HIV vaccines or antiviral therapies. Research has shown that this fragment can elicit an immune response in the body, leading to the production of antibodies that may help neutralize the virus. Additionally, studies have suggested that this fragment could have potential as a diagnostic tool for detecting HIV infection. Overall, HIV (GP120) FRAGMENT (315-329) holds promise for its potential applications in HIV prevention, treatment, and diagnosis.

Relevant articles and documents

Modified epimorphin

Disclosed herein are a modified epimorphin obtained by adding a hydrophilic peptide composed of 5 to 99 amino acids to at least one terminus of a polypeptide containing the functional domain of epimorphin, and a modified epimorphin composed of a polypeptide having a structure wherein a hydrophobic domain adjacent to the C-terminus of the whole-length epimorphin consisting of a coiled coil domain (1) on the N-terminal side, a functional domain (2) at the center, a coiled coil domain (3) on the C-terminal side and the hydrophobic domain (4) adjacent to the C-terminus has been deleted from the whole-length epimorphin, and at least part of amino acids have been deleted from the terminal side of at least one of the coiled coil domains (1) and (3) as well. The invention also discloses a variant modified epimorphin obtained by making partial substitution, deletion and/or insertion of amino acids in the amino acid sequence of the modified epimorphin, wherein the variant maintains the function of the original sequence. The invention further discloses DNAs encoding the modified epimorphin and variant thereof, recombinant vectors containing the DNAs, transformants obtained by introducing the recombinant vectors, and a production method of the modified epimorphin and the variants thereof making use of the transformant.