114991-69-4 Usage
Uses
Used in Pharmaceutical Industry:
3-Methoxy-4-(3-methylbutoxy)benzaldehyde is used as a synthetic intermediate for the development of various pharmaceuticals. Its aldehyde functional group allows it to react with other compounds, facilitating the creation of diverse chemical products with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Methoxy-4-(3-methylbutoxy)benzaldehyde serves as a key component in the synthesis of pesticides and other agrochemicals. Its reactivity contributes to the formation of compounds designed to protect crops and enhance agricultural productivity.
Used in Fragrance Industry:
3-Methoxy-4-(3-methylbutoxy)benzaldehyde is utilized as a building block in the creation of fragrances. Its complex structure and aromatic nature make it suitable for developing unique scents for use in perfumes, cosmetics, and other scented products.
Used in Organic Synthesis:
3-methoxy-4-(3-methylbutoxy)benzaldehyde also has potential applications in organic synthesis, where it may act as a versatile building block for the development of novel molecules with specific properties, contributing to advancements in material science and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 114991-69-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,9,9 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 114991-69:
(8*1)+(7*1)+(6*4)+(5*9)+(4*9)+(3*1)+(2*6)+(1*9)=144
144 % 10 = 4
So 114991-69-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H18O3/c1-10(2)6-7-16-12-5-4-11(9-14)8-13(12)15-3/h4-5,8-10H,6-7H2,1-3H3
114991-69-4Relevant academic research and scientific papers
Novel 2-(substituted benzyl)quinuclidines inhibit human α7 and α4β2 nicotinic receptors by different mechanisms
Arias, Hugo R.,López, Jhon J.,Feuerbach, Dominik,Fierro, Angélica,Ortells, Marcelo O.,Pérez, Edwin G.
, p. 2420 - 2430 (2013/10/01)
This work presents the design and synthesis of a series of novel 2-benzylquinuclidine derivatives, comprising 12 methiodide and 11 hydrochloride salts, and their structural and pharmacological characterization at the human (h) α7 and α4β2 nicotinic receptors (nAChRs). The antagonistic potency of these compounds was tested by Ca2+ influx assays on cells expressing the hα7 or hα4β2 nAChR subtype. To determine the inhibitory mechanisms, additional radioligand binding experiments were performed. The results indicate that the methiodides present the highest affinities for the hα7 nAChR agonist sites, while the same compounds bind preferably to the hα4β2 nAChR ion channel domain. These results indicate that the methiodides are competitive antagonists of the hα7 nAChR but noncompetitive antagonists of the hα4β2 subtype. Docking and molecular dynamics simulations showed that the methiodide derivative 8d binds to the hα7 orthosteric binding sites by forming stable cation-π interactions between the quaternized quinulinuim moiety and the aromatic box in the receptor, whereas compounds 7j and 8j block the hα4β2 AChR ion channel by interacting with a luminal domain formed between the serine (position 6′) and valine (position 13′) rings that overlaps the imipramine binding site.
